H. Demuynck et al., THERAPY-RELATED ACUTE MYELOID-LEUKEMIA WITH T(8-16)(P11-P13) FOLLOWING ANTHRACYCLINE-BASED THERAPY FOR NONMETASTATIC OSTEOSARCOMA, Cancer genetics and cytogenetics, 82(2), 1995, pp. 103-105
A case of therapy-related AML with t(8;16)(p11;p13) 14 months followin
g the end of anthracycline-containing chemotherapy for a nonmetastatic
osteosarcoma of the left tibia is presented. The patient was successf
ully treated with intensive remission-induction chemotherapy. Subseque
ntly, he underwent an uncomplicated allogeneic bone marrow transplanta
tion from his HLA-identical brother and is at present alive and diseas
e-free 10 months after diagnosis of the secondary AML.