MICE DEFICIENT IN GAMMA-DELTA T-CELLS ARE RESISTANT TO LETHAL INFECTION WITH SALMONELLA-CHOLERAESUIS

Authors
EMOTO M NISHIMURA H SAKAI T HIROMATSU K GOMI H ITOHARA S YOSHIKAI Y
Citation
M. Emoto et al., MICE DEFICIENT IN GAMMA-DELTA T-CELLS ARE RESISTANT TO LETHAL INFECTION WITH SALMONELLA-CHOLERAESUIS, Infection and immunity, 63(9), 1995, pp. 3736-3738
Citations number
19
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
63
Issue
9
Year of publication
1995
Pages
3736 - 3738
Database
ISI
SICI code
0019-9567(1995)63:9<3736:MDIGTA>2.0.ZU;2-U
Abstract
Mice deficient in gamma delta T cells were resistant to the gram-negat ive bacteremic sepsis caused by infection with a high dose of Salmonel la choleraesuis accompanied by impaired tumor necrosis factor alpha pr oduction in vivo and in vitro. gamma delta T cells may play a role in the pathogenesis of lethal infection with S. cholernesuis.