THE WALKING-THROUGH PHENOMENON IN PERIPHE RAL ARTERIAL OCCLUSIVE DISEASE

In order to assess the metabolic effects of walking-through phenomenon during treadmill exercise the fluctuations of lactate and pyruvate co ncentration in arterial and popliteal venous blood and the changes in the lactate pyruvate ratio were studied in seven patients with arteria l occlusive disease. During exercise, significant differences in venou s lactate, lactate pyruvate ratio and arterial venous differences in l actate were found in patients with walking-through phenomenon. It is c oncluded that the rate of anaerobic glycolysis is reduced in patients with walking-through phenomen.