CONVENTIONAL DRUG-THERAPY IN INFLAMMATORY BOWEL-DISEASE

Citation
Mg. Griffin et Pb. Miner, CONVENTIONAL DRUG-THERAPY IN INFLAMMATORY BOWEL-DISEASE, Gastroenterology clinics of North America, 24(3), 1995, pp. 509-521
Citations number
89
Categorie Soggetti
Gastroenterology & Hepatology
ISSN journal
08898553
Volume
24
Issue
3
Year of publication
1995
Pages
509 - 521
Database
ISI
SICI code
0889-8553(1995)24:3<509:CDIIB>2.0.ZU;2-G
Abstract
The conventional treatment of inflammatory bowel disease should be dir ected at the extent and severity of disease. One of the many formulati ons of the Ei-aminosalicylic acid preparations should be used for indu ction and maintenance of remission. Glucocorticoids, either topical or systemic, are important adjuncts to therapy. In those patients who ar e unable to be tapered from glucocorticoids, immunosuppressive drugs, such as 6- mercaptopurine and azathioprine, are used as steroid-sparin g agents. Metronidazole's effects in inflammatory bowel disease are de rived from its antimicrobial as well as immunologic properties.