The conventional treatment of inflammatory bowel disease should be dir
ected at the extent and severity of disease. One of the many formulati
ons of the Ei-aminosalicylic acid preparations should be used for indu
ction and maintenance of remission. Glucocorticoids, either topical or
systemic, are important adjuncts to therapy. In those patients who ar
e unable to be tapered from glucocorticoids, immunosuppressive drugs,
such as 6- mercaptopurine and azathioprine, are used as steroid-sparin
g agents. Metronidazole's effects in inflammatory bowel disease are de
rived from its antimicrobial as well as immunologic properties.