T. Ito et al., A NOVEL QUANTITATIVE RECEPTOR AUTORADIOGRAPHY AND IN-SITU HYBRIDIZATION HISTOCHEMISTRY TECHNIQUE USING STORAGE PHOSPHOR SCREEN IMAGING, Journal of neuroscience methods, 59(2), 1995, pp. 265-271
A new technique of image acquisition for quantitative receptor autorad
iography and in situ hybridization histochemistry was developed using
storage phosphor screen imaging. This method was at least 4-5 times fa
ster than conventional film densitometry. Two of the advantages of the
phosphor screen method are high sensitivity and wide linear range of
response. Other aspects of this method were compared with those of con
ventional densitometry. Use of storage phosphor screen imaging will al
low greatly increased speed of pharmacological screening procedures th
at utilize quantitative autoradiography.