BILATERAL ACUTE ANGLE-CLOSURE GLAUCOMA AFTER DEXFENFLURAMINE TREATMENT

We report the case of a patient with narrow angles who had an attack o f bilateral acute angle-closure glaucoma precipitated by dexfenflurami ne, a serotoninergic drug developed for appetite suppression. Although the exact mechanism remains uncertain, the pupillary block observed i n our case may be the result of the serotoninergic or indirect parasym patholytic properties of the drug on the iris sphincter muscle. Seroto nergic psychoactive drugs should be prescribed cautiously in patients with known narrow angles and should be monitored by an ophthalmologist .