CHANGES IN THE TESTES OF ADULT RAMS AFTER BIOPSY OF THE ORGAN

In this paper, the long-term response of the seminiferous parenchyma a fter biopsy of the sexual organs in adult rams is examined. The time i nterval after biopsy ranged from 2-3 weeks to 2,3,4,5,7,8,9, and 12 mo nths. The findings were evaluated by means of histological and electro n-microscopical methods. The results of the experiments confirmed seve re injury of the organs, with persistent degenerative changes to the g erminal cells. Biopsy results indicated serious injury to the germinal epithelium of the testes, with a subsequent cessation or even destruc tion of spermiogenesis in the attached organ. Unilateral biopsy also c aused secondary disturbances to the contralateral testis since, at lat er intervals, findings of diffuse calcification foci were also found i n the contralateral testis. The irreversibility of the induced changes resulted in permanent injury or loss of reproductive ability in the a nimals.