Smoke is a mixture of particles and gaseous chemicals of varying physi
cal and chemical properties. When inhaled these produce the characteri
stic features of smoke-inhalational injury. Although heat is produced
in fires it is the chemical agents which cause the damage to the airwa
ys and the lungs. Mortality and morbidity are closely related to pulmo
nary injury and thus to the particulate and chemical nature of smoke.
Moreover, there seems to be a potentiating effect, in that the particl
es worsen the toxicity of the chemicals present.