EXFOLIATIVE DERMATITIS ASSOCIATED WITH DILTIAZEM

Background: Exfoliative dermatitis due to calcium channel blockers is a known but infrequent response. Case Report: A 77-year-old woman bega n treatment with diltiazem for angina pectoris. Three days later, seve re exfoliative dermatitis developed. Conclusion: The present case and the others previously reported emphasize the need for greater awarenes s of the occurrence of adverse cutaneous reactions including toxic epi dermal necrolysis, Stevens-Johnson syndrome and cutaneous vasculitis d ue to calcium channel blockers including diltiazem.