EVOLUTIONARY RELATIONSHIPS AND SEQUENCE VARIATION OF ALPHA-AMYLASE VARIANTS ENCODED BY DUPLICATED GENES IN THE AMY LOCUS OF DROSOPHILA-MELANOGASTER

Citation
N. Inomata et al., EVOLUTIONARY RELATIONSHIPS AND SEQUENCE VARIATION OF ALPHA-AMYLASE VARIANTS ENCODED BY DUPLICATED GENES IN THE AMY LOCUS OF DROSOPHILA-MELANOGASTER, Genetics, 141(1), 1995, pp. 237-244
Citations number
42
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00166731
Volume
141
Issue
1
Year of publication
1995
Pages
237 - 244
Database
ISI
SICI code
0016-6731(1995)141:1<237:ERASVO>2.0.ZU;2-Q
Abstract
To infer the genealogical relationships of alpha-amylase electromorphs of Drosophila melanogaster, we determined the nucleotide sequences of a collection of electromorphs sampled throughout the world. On averag e there were 1.0 amino acid substitutions between identical electromor phs and 3.9 between different electromorphs, respectively. We found th at the evolution of AMY(1) through AMY(6) electromorphs occurred by se quential accumulation of single amino acid substitutions each causing one charge difference. The nucleotide diversities at synonymous sites within Amy(1),Amy(2),Amy(3),Amy(4) and Amy(6) were 0.0321, 0.0000, 0.0 355, 0.0059 and 0.0030, respectively. We also obtained evidence of gen etic exchanges, such as intrachromosomal recombination, interchromosom al recombination or gene conversion, between the mio duplicated Amy ge nes as well as among the alleles.