HIGH RENIN ARTERIAL-HYPERTENSION DUE TO OCCLUSION OF THE ADRENAL VEINS IN THE RAT

The direct adreno-renal vascular connection allows precise control of the kidney function by hormones produced by the adrenal gland, without any significant changes in their content in the whole blood. The purp ose of the present study is to investigate the effect of the increased blood now through the vascular network on the blood pressure. In twel ve Wistar rats the central adrenal veins were ligated bilaterally. Thi s procedure resulted in chronic increase in systolic blood pressure. T his model of arterial hypertension is characterized by high plasma ren in activity and normal aldosterone plasma concentration.