RIFAMPICIN INACTIVATION BY BACILLUS SPECIES

Authors
DABBS ER YAZAWA K TANAKA Y MIKAMI Y MIYAJI M ANDERSEN SJ MORISAKI N IWASAKI S SHIDA O TAKAGI H KADOWAKI K
Citation
Er. Dabbs et al., RIFAMPICIN INACTIVATION BY BACILLUS SPECIES, Journal of antibiotics, 48(8), 1995, pp. 815-819
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
48
Issue
8
Year of publication
1995
Pages
815 - 819
Database
ISI
SICI code
0021-8820(1995)48:8<815:RIBBS>2.0.ZU;2-R
Abstract
The ability of strains of Bacillus, Staphylococcus, Pseudomonas, and E scherichia coli to inactivate rifampicin was tested. Most Bacillus str ains were found to inactivate rifampicin. Two modes of inactivation we re identified; one was phosphorylation and the other involved decolori zation. Presence or absence of either mechanism appeared unrelated to the phylogenetic relatedness of strains. None of the other organisms c ould inactivate this antibiotic.