The discovery of polymeric DNA in charred wheat grains and other burnt
plant remains prompted us to examine a set of cremated bones for the
presence of ancient DNA. Extracts of cremated bones from an early Bron
ze Age cemetery cairn were analysed by hybridization probing and the p
olymerase chain reaction. Hybridization with two probes targeting huma
n DNA resulted in strong positive signals. Polymerase chain reactions
directed at a multicopy sequence in human nuclear DNA were successful,
extracts of five burials giving amplification products of the expecte
d size. Exploitation of ancient DNA in cremated bones could be of grea
t value in archaeology as it may enable information pertaining to sex
and kinship to be obtained from fragmented material.