Ss. Wong et Jwm. Lawton, ANTIPROTEINASE-3 ANTIBODY-ACTIVITY IN A PATIENT WITH PRIMARY SCLEROSING CHOLANGITIS - CLINICAL REMISSION FOLLOWING URSODEOXYCHOLIC ACID THERAPY, Journal of gastroenterology and hepatology, 11(12), 1996, pp. 1161-1163
Primary sclerosing cholangitis is rare among Chinese. We report on a 7
1 year old male patient who presented with clinical features consisten
t with the disorder. Subsequent investigations confirmed the diagnosis
. The patient was found to have anti-neutrophil cytoplasmic antibodies
with specificity against proteinase 3. Treatment with ursodeoxycholic
acid resulted in clinical remission and disappearance of the antibodi
es.