V. Jordan et al., THE INCIDENCE OF HYPEREMESIS-GRAVIDARUM IS INCREASED AMONG PACIFIC ISLANDERS LIVING IN WELLINGTON, New Zealand medical journal, 108(1006), 1995, pp. 342-344
Aims. To compare the incidence of hyperemesis gravidarum among Pacific
Islanders living in Wellington with nonPacific Islanders and to inves
tigate some properties of the disorder. Methods. Data were collected o
n all first time admissions to Wellington Women's Hospital for hyperem
esis gravidarum over a 5-year period. Women were classified as having
severe hyperemesis gravidarum if abnormalities of serum electrolytes a
nd liver function tests results were present and as less severe if the
se abnormalities were absent. Almost all women had ketonuria. Mantel-H
aenszel odds ratios, chi(2) analysis and Fisher's 2-tailed exact test
were used for statistical analysis. Results. The proportion of hyperem
esis gravidarum patients who were Pacific Islanders was significantly
increased when compared to their proportion in a control group (p<0.01
). The difference remained significant when the hyperemesis patients w
ere divided into less and more severe. Abnormal thyroid function test
results were more common among Pacific Island patients than among nonP
acific Island patients. This difference was significant (p<0.01) only
in the less severe group. Conclusion. The incidence of hyperemesis gra
vidarum is significantly increased among Pacific Island women (especia
lly Samoans) living in Wellington and is often associated with abnorma
lities of thyroid function test results.