A NOVEL BIOSYNTHETIC ROUTE TO PREGNANES IN THE MARINE SPONGE AMPHIMEDON COMPRESSA

Authors
KERR RG KELLY K SCHULMAN A
Citation
Rg. Kerr et al., A NOVEL BIOSYNTHETIC ROUTE TO PREGNANES IN THE MARINE SPONGE AMPHIMEDON COMPRESSA, Journal of natural products, 58(7), 1995, pp. 1077-1080
Citations number
8
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
58
Issue
7
Year of publication
1995
Pages
1077 - 1080
Database
ISI
SICI code
0163-3864(1995)58:7<1077:ANBRTP>2.0.ZU;2-3
Abstract
A novel degradative route to pregnanes has been elucidated in the mari ne sponge Amphimedon compressa, 22-Dehydrosterols, common in the diet of sponges, are the precursors to pregnanes and apparently are degrade d by a mechanism analogous to the dealkylation of phytosterols to chol esterol.