The purpose of the study was to determine the glucocorticoid reserve i
n patients with AIDS. Thirty patients with AIDS, who were not critical
ly ill, were chosen consecutively and studied prospectively over a 1-y
ear period with cosyntropin-stimulation testing. All patients showed n
ormal glucocorticoid response to cosyntropin stimulation. Clinical adr
enal insufficiency is uncommon in patients with AIDS who are not criti
cally ill.