GONADOBLASTOMA WITH COEXISTENT FEATURES OF MIXED GERM CELL-SEX CORD STROMA TUMOR - A CASE-REPORT

Gonadoblastoma and mixed germ cell-sex cord stroma tumor have been wid ely recognized as two separate entities on the basis of both clinical and pathological features. The typical morphological pattern of both t umor types was found by us to coexist in the same gonadal tumor in a 1 4-year-old 46,XY phenotypically female subject who also had a contrala teral dysgerminoma. A subserous implant showing the mixed germ cell-se x cord pattern of the primary tumor was detected in the uterine body. Following therapy the patient is alive and well after a 7-year follow- up. The distinction between gonadoblastoma and mixed germ cell-sex cor d stroma tumor requires discussion.