NAVIGATOR - TOOLS FOR INFORMAL STRUCTURE-ACTIVITY RELATIONSHIP DISCOVERY

Navigator is a molecular database visualization sl stem, designed to s upport exploratory data analysis and informal structure-activity, rela tionship studies. In addition to the operations commonly found in chem ical database systems, it provides new tools that facilitate substitue nt analysis and help elucidate the relationships among similar molecul es and between related assays. Navigator's capabilities include two wa ys of displaying the relationships between analogs, mouse-sensitive ch arts of sets of molecules, mouse-sensitive plots of assay relationship s, and access to a system for three-dimensional quantitative structure -activity relationship discovery. Navigator's mouse-based user interfa ce provides a one-object/one-window paradigm that makes data manipulat ion easy even for inexperienced users. Navigator runs on Silicon Graph ics workstations.