Sc. Shoner et al., A MODEL FOR THE LOW-SPIN, NONHEME, THIOLATE-LIGATED IRON SITE OF NITRILE HYDRATASE, Inorganic chemistry, 34(18), 1995, pp. 4517-4518
A synthetic analogue of nitrile hydratase, [Fe-III(ADIT)(2)]-Cl (2), i
s described. Nitrile hydratase is the first and only current example o
f a metalloenzyme containing a single non-heme Fe in a mixed N/S-ligat
ed coordination site. Like the enzyme, 2 possesses short Fe-S distance
s, EPR parameters indicative of an S = 1/2 ground state, and a single
band near 710 nm in its electronic spectrum. Low-spin complexes of thi
s type are extremely rare.