The Hamilton Depression Rating Scale was applied to 60 depressed inpat
ients diagnosed using the Composite International Diagnostic Interview
. The information to rate the scale was obtained with a semistructured
interview to standardize the scale administration method. Items were
factorized using principal components analysis with Varimax rotation.
Three factors were obtained with the simulation method, accounting for
47% of variance. The first includes the core symptoms of depression.
The symptoms of patients having an isolated mood disorder were compare
d with those having comorbidity with other diagnoses. The comorbidity
did not affect the first factor but modified the second factor (anxiet
y) and the third factor (insomnia).