Study Design. This is a report of a patient with acute spinal epidural
hematoma taking aspirin, 250 mg/day. Objective. To describe the assoc
iation of spinal epidural hematoma and aspirin. Summary of Background
Data. In about 50% of patients, the cause of acute spinal epidural hem
atoma is obscure. Analysis of possible mechanisms is necessary. Method
s. Diagnostic lumbar puncture, suboccipital myelography, and surgical
removal of the hematoma was performed. Results. Increased bleeding was
noticed during these procedures. Bleeding time was normal 6 days afte
r discontinuance of aspirin. Conclusion. Because aspirin is widely use
d, its role in causing spinal epidural hematoma will remain conjectal.
For the present patient, however, it was postulated that aspirin had
a major impact on the extent of the epidural bleeding. There should be
awareness of a possible link between aspirin and spinal epidural hema
toma.