DERIVATIVE UV-SPECTROPHOTOMETRIC DETERMINATION OF BINARY-MIXTURES OF PROCAINE HYDROCHLORIDE WITH BENZOIC-ACID, PYRIDOXINE HYDROCHLORIDE AND4-AMINOBENZOIC ACID, FROM PHARMACEUTICAL PREPARATIONS

Authors
SURMEIAN M CIOHODARU G IONESCU MS COSOFRET VV
Citation
M. Surmeian et al., DERIVATIVE UV-SPECTROPHOTOMETRIC DETERMINATION OF BINARY-MIXTURES OF PROCAINE HYDROCHLORIDE WITH BENZOIC-ACID, PYRIDOXINE HYDROCHLORIDE AND4-AMINOBENZOIC ACID, FROM PHARMACEUTICAL PREPARATIONS, Revue Roumaine de Chimie, 40(2), 1995, pp. 111-117
Citations number
25
Categorie Soggetti
Chemistry
Journal title
Revue Roumaine de Chimie → ACNP
ISSN journal
00353930
Volume
40
Issue
2
Year of publication
1995
Pages
111 - 117
Database
ISI
SICI code
0035-3930(1995)40:2<111:DUDOBO>2.0.ZU;2-B
Abstract
The UV-derivative spectrophotometric method, the zero-crossing techniq ue, was used for simultaneous determination of binary mixtures of proc aine hydrochloride with: benzoic acid, pyridoxine hydrochloride and 4- aminobenzoic acid. The results obtained for 4-aminobenzoic acid, produ ced by thermal degradation of procaine hydrochloride from Gerovital H- 3(R) - ampoules, were compared with those obtained by UV-densitometric measurement after thin layer chromatographic separation.