INVERSION TRANSITIONS OF AMINO GROUP IN THE LOCAL-ANESTHETIC BENZOCAINE

From the two wagging frequencies of p-amino group identified by infrar ed and Laser-Raman spectroscopy in the local anesthetic benzocaine, th e inversion barrier height and optimum inversion angle of this group w ere calculated. The different energy levels of inversion and their ass ociated frequencies were also determined. The calculations were carrie d out following two procedures: resolving the torsional Schrodinger eq uation and by Harmonic approximation of vibration.