K. Akiyoshi et al., STABILIZATION OF INSULIN UPON SUPRAMOLECULAR COMPLEXATION WITH HYDROPHOBIZED POLYSACCHARIDE NANOPARTICLE, Chemistry Letters, (8), 1995, pp. 707-708
The hydrogel nanoparticle that was formed by self-assembly of choleste
rol-bearing pullulan complexed with 5 - 10 insulin monomers in water.
Biocolloidal and thermal stability of insulin drastically increased up
on the supramolecular assembly with the hydrophobized polysaccharide.