Proglycinins containing multiple modifications, that is, with two kind
s of single modifications, designed previously to improve food functio
ns, were assessed for,ability to form proper conformations. This was d
one to discover the modification tolerability of proglycinin. Based on
our results, three new criteria are proposed for judging formation of
proper conformations. Our results suggest that proglycinin molecules
tolerate different combinations of single modifications without misfol
ding.