M. Curatolo et al., A MULTIFACTORIAL ANALYSIS TO EXPLAIN INADEQUATE SURGICAL ANALGESIA AFTER EXTRADURAL BLOCK, British Journal of Anaesthesia, 75(3), 1995, pp. 274-281
A multivariate analysis of inadequate extradural analgesia was carried
out prospectively on 1051 patients undergoing lumbar extradural anaes
thesia for surgery performed on structures innervated by T10-S5. Ninet
y-six patients (9%) experienced pain during surgery. Age, extradural f
entanyl, diazepam sedation and duration of surgery had no significant
influence. We found some weak evidence that the type of surgery affect
s the risk of feeling pain. The probability of pain increased with inc
reasing weight, except in overweight women, and was significantly grea
ter for both shorter and taller patients, relative to patients of aver
age height. The probability of pain decreased with increasing dose of
local anaesthetic, increasing spread of extradural analgesia, addition
of adrenaline, and fentanyl or thiopentone sedation. In conclusion, p
atient-, surgery- and anaesthesia-related factors influence the risk o
f inadequate extradural analgesia. If such factors are taken into acco
unt, an increase in the success rate may be anticipated.