COMPARISON OF DESFLURANE AND ISOFLURANE IN ANESTHESIA FOR DENTAL SURGERY

We studied 50 ASA I-II patients, aged 18-65 yr, undergoing elective or ofacial surgery. Anaesthesia was induced with fentanyl and propofol, a nd maintained with 66% nitrous oxide in oxygen and either desflurane o r isoflurane to compare recovery characteristics and cardiovascular st ability. Cardiovascular responses to induction, intubation and incisio n were similar with both agents, although the increase in heart rate i n response to intubation was less marked in the desflurane group. Maxi mum end-tidal concentrations of desflurane required were 4.0-10.6% (me an 6.8%) compared with maximum isoflurane concentrations of 1.1-2.3% ( mean 1.6%). Mean duration of anaesthesia was 46 (SD 17.9) min (range 2 5-89 min) in the desflurane group and 41 (11.5) (23-60) min in the iso flurane group. Times to extubation were 6.7 (2.1) (3-10) min and 11.3 (4.1) (5-23) min, to eye opening 6.8 (2.2) (3-11) min and 12.7 (6.9) ( 7-37) min, to stating date of birth 9.0 (2.3) (4-12) min and 15.0 (6.9 ) (8-39) and to discharge from the recovery room 45 (11.6) (22-80) min and 64 (20.9) (28-134) min, for the desflurane and isoflurane groups, respectively (all P < 0.0001). No serious complications occurred in a ny patient.