Mechanical complications of acute myocardial infarction include papill
ary muscle rupture with severe mitral regurgitation, ventricular septa
l rupture with acute ventricular septal defect, acute and subacute fre
e-mall rupture, and hemodynamically significant right ventricular infa
rction. Although such complications are infrequent, their importance i
s underscored because of the potential ability to correct them with ea
rly diagnosis and appropriate treatment. The diagnosis necessitates a
high degree of suspicion based on clinical clues and rapid diagnostic
testing. Bedside two-dimensional echocardiography, sometimes with tran
sesophageal echocardiography, is most commonly used to diagnose or exc
lude these complications. Patients suspected of having a mechanical co
mplication of myocardial infarction should be urgently transferred to
a medical center experienced in the management of these problems. For
deteriorating patients without identifiable mechanical complications,
coronary angiography and reperfusion with direct angioplasty should be
considered.