M. Parkkari et al., THE TREATMENT OF ENDOPHTHALMITIS AFTER CATARACT-SURGERY - REVIEW OF 26 CASES, Journal of ocular pharmacology and therapeutics, 11(3), 1995, pp. 349-359
A retrospective study of 26 cases of postoperative endophthalmitis occ
urring after extracapsular cataract extraction and lens implantation w
as conducted between January 1989 and December 1992. Twenty-one of the
26 cases (81 %) were diagnosed within two weeks after surgery. The mo
st common organism isolated was Staphylococcus saprophyticus (23 %). A
fter the bacterial samples had been taken, cefotaxime or gentamicin wa
s injected into anterior chamber and vitreous space. The therapy regim
en consisted of topical tobramycin, Polysporin(R) (polymyxinsulfate, n
eomycinsulfate and gramicidin), dexamethasone and atropine and parabul
bar cefotaxime, netilmicin and betamethasone. Cefotaxime or, alternati
vely, clindamycin, ciprofloxacin and prednisolone were given systemica
lly. The final visual acuity of 20/40 or more was obtained in 15 cases
(58 %). Twenty-one patients (81 %) achieved a visual acuity of 20/400
or better. Three patients had no light perception after the treatment
of endophthalmitis. Silk as suture material in wound closure and rupt
ure of the posterior capsule were found to be risk factors in the deve
lopment of endophthalmitis. The results of the present study show that
effective drug treatment also results in good visual outcome.