CLONING AND SEQUENCING OF A CDNA-ENCODING THE CANINE HSP27 PROTEIN

Authors
LARSEN JK GERTHOFFER WT HICKEY E WEBER LA
Citation
Jk. Larsen et al., CLONING AND SEQUENCING OF A CDNA-ENCODING THE CANINE HSP27 PROTEIN, Gene, 161(2), 1995, pp. 305-306
Citations number
12
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
161
Issue
2
Year of publication
1995
Pages
305 - 306
Database
ISI
SICI code
0378-1119(1995)161:2<305:CASOAC>2.0.ZU;2-0
Abstract
The nucleotide (nt) sequence encoding a 27-kDa heat-shock protein (HSP 27) was determined from cDNAs cloned from a canine smooth muscle libra ry. The primary structure deduced from the nt sequence reveals a 209-a mino-acid protein having 86-89% identity with human, mouse, rat and ha mster small HSP. Similar to human HSP27, the canine protein contains t hree Ser residues that are potential MAPKAP kinase II substrates.