POPULATION-DYNAMICS OF FELINE-IMMUNODEFICIENCY-VIRUS WITHIN CAT POPULATIONS

A deterministic model was constructed for studying the circulation of Feline Immunodeficiency Virus (FIV), a feline retrovirus homologous to Human Immunodeficiency Virus (HIV), within populations of domestic ca ts. The model has been tested with data generated by a long-term study of several natural cat populations. Simulations and a study of stabil ity show that once introduced, the retrovirus is maintained within the population, with a stable equilibrium stage reached by both numbers o f susceptible and infected individuals. An estimation of parameters in dicates that the transmission rate is low and depends of the structure of the population. In addition, FIV has a low impact on the populatio n in that the total number of cats at equilibrium when this virus is p resent is almost always equal to the habitat carrying capacity in the absence of the virus. Those results, in agreement with other observati ons, suggest that FIV originally arose in the distant past. (C) 1995 A cademic Press Limited