BONE-MARROW PURGING WITH DIBUTYL PHTHALATE - EXPERIMENTAL BASIS AND APRELIMINARY CLINICAL-APPLICATION

Authors
WU CT KE Y PEI XT TANG AP WANG FS WANG LS
Citation
Ct. Wu et al., BONE-MARROW PURGING WITH DIBUTYL PHTHALATE - EXPERIMENTAL BASIS AND APRELIMINARY CLINICAL-APPLICATION, Leukemia research, 19(8), 1995, pp. 557-560
Citations number
11
Categorie Soggetti
Oncology,Hematology
Journal title
Leukemia research → ACNP
ISSN journal
01452126
Volume
19
Issue
8
Year of publication
1995
Pages
557 - 560
Database
ISI
SICI code
0145-2126(1995)19:8<557:BPWDP->2.0.ZU;2-5
Abstract
It has been found recently that di-n-butyl phthalate (DBP) possesses a new pharmacological activity in the selective elimination of tumor ce lls from marrow. In combination with long-term liquid culture of marro w cells in vitro, DBP purged autologous bone marrow transplantation ha s first been applied to a case of acute myeloid leukemia at the first complete remission with successful reconstitution of hematopoiesis.