ANTI 70 KDA HEAT-SHOCK PROTEIN ANTIBODIES IN SERA OF PATIENTS AFFECTED BY AUTOIMMUNE AND NON-AUTOIMMUNE THYROID-DISEASES

Authors
PAGGI A DIPRIMA MA PAPARO BS PELLEGRINO C FARALLI AR SINOPOLI MT LERI O
Citation
A. Paggi et al., ANTI 70 KDA HEAT-SHOCK PROTEIN ANTIBODIES IN SERA OF PATIENTS AFFECTED BY AUTOIMMUNE AND NON-AUTOIMMUNE THYROID-DISEASES, Endocrine research, 21(3), 1995, pp. 555-567
Citations number
16
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Endocrine research → ACNP
ISSN journal
07435800
Volume
21
Issue
3
Year of publication
1995
Pages
555 - 567
Database
ISI
SICI code
0743-5800(1995)21:3<555:A7KHPA>2.0.ZU;2-N
Abstract
Twenty eight patients (25F, 3M) affected by autoimmune and non-autoimm une thyroid diseases were studied. HSP 70 antibodies were present in 2 1.4% of patients. Five of them were affected by Graves' disease and on e by De Quervain's thyroiditis. The HSP 70 antibodies mean values of p atients were significantly higher than the normals ( p < 0.05). This d atum was confirmed by Western blotting. The presence of HSP 70 antibod ies in the sera of those patients may support the link between the pro tein and the thyroid autoimmune processes.