Aspergillosis of the central nervous system (CNS) is an uncommon infec
tion, mainly occurring in immunocompromised patients. Beside cerebral
involvement spinal cord lesions are extremely rare. To our know ledge,
aspergillosis initially presenting,vith acute paraplegia due to mycot
ic thrombosis of the anterior spinal artery in a formerly healthy pati
ent has, so far,not been reported. Neither a primary focus nor an unde
rlying disease had been detected.