A STEREOSELECTIVE FORMAL SYNTHESIS OF (+ -)-(GAMMA)-LYCORANE/

Authors
ANGLE SR BOYCE JP
Citation
Sr. Angle et Jp. Boyce, A STEREOSELECTIVE FORMAL SYNTHESIS OF (+ -)-(GAMMA)-LYCORANE/, Tetrahedron letters, 36(35), 1995, pp. 6185-6188
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
35
Year of publication
1995
Pages
6185 - 6188
Database
ISI
SICI code
0040-4039(1995)36:35<6185:ASFSO(>2.0.ZU;2-F
Abstract
Compound 11, a common intermediate in several syntheses of (+/-)-gamma -lycorane, was prepared, from commercially available N-triisopropylsil yl pyrrole, in 13 steps and overall 34% yield. The key step of the syn thesis involved the diastereoselective hydrogenation of a substituted pyrrole ring.