CHEMOSELECTIVE GLYCOSYLATIONS .1. DIFFERENCES IN SIZE OF ANOMERIC LEAVING GROUPS CAN BE EXPLOITED IN CHEMOSELECTIVE GLYCOSYLATIONS

Authors
BOONS GJ GEURTSEN R HOLMES D
Citation
Gj. Boons et al., CHEMOSELECTIVE GLYCOSYLATIONS .1. DIFFERENCES IN SIZE OF ANOMERIC LEAVING GROUPS CAN BE EXPLOITED IN CHEMOSELECTIVE GLYCOSYLATIONS, Tetrahedron letters, 36(35), 1995, pp. 6325-6328
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
35
Year of publication
1995
Pages
6325 - 6328
Database
ISI
SICI code
0040-4039(1995)36:35<6325:CG.DIS>2.0.ZU;2-8
Abstract
We have developed a novel chemoselective glycosylation strategy. This glycosylation strategy is based on the fact that the glycosyl reactivi ty of an anomeric thiol group can be control by the bulkiness of this group whereby we have produced a new range of differentially reactive coupling substrates. The new approach will enable complex oligosacchar ides of biological importance to be prepared in a highly convergent ma nner.