DESIGN AND SYNTHESIS OF A NOVEL EPOXIDE-CONTAINING PYRROLO[2,1-C][1,4]BENZODIAZEPINE (PBD) VIA A NEW CYCLIZATION PROCEDURE

Authors
WILSON SC HOWARD PW THURSTON DE
Citation
Sc. Wilson et al., DESIGN AND SYNTHESIS OF A NOVEL EPOXIDE-CONTAINING PYRROLO[2,1-C][1,4]BENZODIAZEPINE (PBD) VIA A NEW CYCLIZATION PROCEDURE, Tetrahedron letters, 36(35), 1995, pp. 6333-6336
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
35
Year of publication
1995
Pages
6333 - 6336
Database
ISI
SICI code
0040-4039(1995)36:35<6333:DASOAN>2.0.ZU;2-M
Abstract
The synthesis of a potential DNA-crosslinking pyrrolo[2,1-c][1,4]benzo diazepine (PBD) substituted at the C8-position with a 2,3-epoxypropane oxy moiety using a new cyclization procedure is described.