BIFUNCTIONAL RECEPTORS - RATE ACCELERATIONS OF OXIDATIVE DECARBOXYLATION OF PYRUVATE BY THYMINE-THIAZOLIUM IN THE PRESENCE OF A MELAMINE DERIVATIVE BEARING A GUANIDINIUM ION

Authors
TAKAKI A UTSUMI K KAJIKI T KUROI T NABESHIMA T YANO Y
Citation
A. Takaki et al., BIFUNCTIONAL RECEPTORS - RATE ACCELERATIONS OF OXIDATIVE DECARBOXYLATION OF PYRUVATE BY THYMINE-THIAZOLIUM IN THE PRESENCE OF A MELAMINE DERIVATIVE BEARING A GUANIDINIUM ION, Chemistry Letters, (1), 1997, pp. 75-76
Citations number
14
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
1
Year of publication
1997
Pages
75 - 76
Database
ISI
SICI code
0366-7022(1997):1<75:BR-RAO>2.0.ZU;2-P
Abstract
It was found that melamine derivatives bearing a guanidinium ion assem ble a thymine-thiazolium ion and pyruvate in close proximity via hydro gen bonds to enhance the rate of the oxidative decarboxylation in CHCl 3-MeCN (9 : 1 v/v), where the guanidinium ion not only binds pyruvate but also activates it.