HEMATOLOGICAL-CHANGES IN THE GARDEN LIZARD, CALOTES-NEMORICOLA DUE TOTHE DEFENSIVE SECRETION OF THE GRASSHOPPER, POECILOCERUS-PICTUS

Citation
Y. Sreenivasulu et Gr. Reddy, HEMATOLOGICAL-CHANGES IN THE GARDEN LIZARD, CALOTES-NEMORICOLA DUE TOTHE DEFENSIVE SECRETION OF THE GRASSHOPPER, POECILOCERUS-PICTUS, Drug and chemical toxicology, 18(2-3), 1995, pp. 223-229
Citations number
18
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy",Chemistry
ISSN journal
01480545
Volume
18
Issue
2-3
Year of publication
1995
Pages
223 - 229
Database
ISI
SICI code
0148-0545(1995)18:2-3<223:HITGLC>2.0.ZU;2-R
Abstract
Defensive secretion of the Grasshopper, Poecilocerus pictus produced s ignificant changes in the blood components of the predator lizard, C. nemoricola. The red blood cell (RBC) count, haemoglobin (Hb) concentra tion, packed cell volume (PCV), mean corpuscular haemoglobin (MCH), me an corpuscular haemoglobin concentration (MCHC) and white blood cell ( WBC) count decreased greatly, whereas mean corpuscular volume (MCV) sh owed significant increase following the administration of lethal dose of defensive secretion. These changes however were found to be reversi ble toward control levels in the lizards injected with sublethal dose. Disrupted erythropoeitic activity in lizards by the cardenolides in t he defensive secretion was suggested.