LIPOFUSCIN PIGMENT IN CEREBELLAR PURKINJE NEURONS AND CHOROID-PLEXUS EPITHELIAL-CELLS OF MACAQUE MONKEYS WITH PLASMODIUM-KNOWLESI CEREBRAL MALARIA - AN ELECTRON-MICROSCOPIC OBSERVATION
Mo. Ibiwoye et al., LIPOFUSCIN PIGMENT IN CEREBELLAR PURKINJE NEURONS AND CHOROID-PLEXUS EPITHELIAL-CELLS OF MACAQUE MONKEYS WITH PLASMODIUM-KNOWLESI CEREBRAL MALARIA - AN ELECTRON-MICROSCOPIC OBSERVATION, Journal of veterinary medicine. Series B, 42(3), 1995, pp. 140-146
Experimental infection of rhesus monkeys (Macaca mulatta) with a virul
ent (W1) strain of Plasmodium knowlesi resulted in cerebral malaria. E
lectron microscopical examination of the brain revealed large numbers
of intracytoplasmic lipofuscin pigment deposits in cerebellar Purkinje
neurones and choroid plexus epithelium of the lateral ventricle. This
lesion may be part of the nervous system response to ischaemic hypoxi
a.