R. Jolanki et al., OCCUPATIONAL ALLERGIC CONTACT-DERMATITIS CAUSED BY EPOXY DIACRYLATE IN ULTRAVIOLET-LIGHT-CURED PAINT, AND BISPHENOL-A IN DENTAL COMPOSITE RESIN, Contact dermatitis, 33(2), 1995, pp. 94-99
Allergic concact dermatitis (ACD) caused by epoxy di(meth)acrylates or
bisphenol A is rare. Here 2 such cases are reported. A dental assista
nt had allergic contact dermatitis (ACD) caused by bisphenol A contain
ed in dental composite resin (DCR) products based on epoxy dimethacryl
ate. The contact allergy was verified by allergic patch test reactions
to bisphenol A and 2 DCRs. The DCRs giving allergic reactions were an
alyzed, and 0.014-0.015% of bisphenol A was detected. Occupational ACD
caused by bisphenol A in dental composite resins has not been describ
ed before. The other patient was a male process worker in a paint fact
ory. He was sensitized by an epoxy diacrylate, bis[4-(2-hydroxy-3-acry
loxypropoxy)phenyl]-propane (BIS-GA), and other acrylate compounds con
tained in raw materials of ultraviolet-light-curable paint. The epoxy
diacrylate gave an allergic patch test reaction down to 0.016% in pet.
He also had an allergic patch test reaction to several other acrylate
compounds, 2-hydroxyethyl acrylate, 2-hydroxypropyl acrylate, 1,4-but
anediol diacrylate, 1,6-hexanediol diacrylate, diethyleneglycol diacry
late, triethylene glycol diacrylate, and tripropylene glycol diacrylat
e, indicating cross and/or concomitant sensitization.