The present study summarizes information on toothpaste composition as
supplied by the manufacturers. The survey covered 48 items, virtually
all toothpastes offered for sale in Finland. It was concluded that the
toothpastes are not entirely safe to use, because almost 50% of the p
roducts studied contained a total of some 30 compounds widely recogniz
ed as allergens. According to the literature, the most common allergen
s in toothpastes are flavours (e.g., cinnamic aldehyde, cinnamon oil a
nd peppermint) and preservatives. Symptoms include stomatitis, cheilit
is, glossitis, gingivitis, perioral dermatitis and immediate hypersens
itivity.