A number of therapeutic options to control pain, maintain function and
decrease disability are available for older patients with osteoarthri
tis. The indication for pharmacological therapy should be restricted t
o periods with pain. Great attention should be given to nonpharmacolog
ical interventions such as education, exercise, lifestyle modification
and emotional support. If medication is necessary, most patients requ
ire only pure analgesics such as paracetamol (acetaminophen); nonstero
idal anti-inflammatory drugs (NSAIDs) should be used if patients do no
t respond to simpler measures. All medication should be carefully moni
tored considering the frequency of adverse drug reactions in older pat
ients.