H. Iwahashi et al., THE CORRELATIVE EVIDENCE SUGGESTING THAT TREHALOSE STABILIZES MEMBRANE-STRUCTURE IN THE YEAST SACCHAROMYCES-CEREVISIAE, Cellular and molecular biology, 41(6), 1995, pp. 763-769
The contribution of trehalose and hsp 104 to membrane fluidity and the
mobility of non-freezing cell water were examined on the basis of who
le cell NMR analysis of the yeast Saccharomyces cerevisiae. Membrane f
luidity was dependent on the accumulation of trehalose not hsp 104 and
non-freezing cell water was dependent on the accumulation of hsp 104
not trehalose. Thus, the correlative evidence suggesting that trehalos
e protects yeast cells from temperature extremes by stabilizing the me
mbrane structure was observed in vivo.