THE CORRELATIVE EVIDENCE SUGGESTING THAT TREHALOSE STABILIZES MEMBRANE-STRUCTURE IN THE YEAST SACCHAROMYCES-CEREVISIAE

Authors
IWAHASHI H OBUCHI K FUJII S KOMATSU Y
Citation
H. Iwahashi et al., THE CORRELATIVE EVIDENCE SUGGESTING THAT TREHALOSE STABILIZES MEMBRANE-STRUCTURE IN THE YEAST SACCHAROMYCES-CEREVISIAE, Cellular and molecular biology, 41(6), 1995, pp. 763-769
Citations number
28
Categorie Soggetti
Cell Biology",Biology
Journal title
Cellular and molecular biology → ACNP
ISSN journal
01455680
Volume
41
Issue
6
Year of publication
1995
Pages
763 - 769
Database
ISI
SICI code
0145-5680(1995)41:6<763:TCESTT>2.0.ZU;2-R
Abstract
The contribution of trehalose and hsp 104 to membrane fluidity and the mobility of non-freezing cell water were examined on the basis of who le cell NMR analysis of the yeast Saccharomyces cerevisiae. Membrane f luidity was dependent on the accumulation of trehalose not hsp 104 and non-freezing cell water was dependent on the accumulation of hsp 104 not trehalose. Thus, the correlative evidence suggesting that trehalos e protects yeast cells from temperature extremes by stabilizing the me mbrane structure was observed in vivo.