DURABILITY OF THE MITROFLOW PERICARDIAL VALVE AT 10 YEARS

From 1983 to 1992, 366 patients received 407 Mitroflow pericardial val ves. Mean age was 62 +/- 14 years. Average follow-up was 72 +/- 28 mon ths. Total follow-up was 1,791 patient-years. Overall survival in all. patients was 77.2% +/- 2.2% at 5 years and 56.2% +/- 6.4% at 10 years . Freedom from structural valve deterioration was 95% +/- 1.2% and 36. 7% +/- 8.1% at 5 and 10 years for all valves, 96.9% +/- 1.3% and 39.2% +/- 9.8% for aortic valve replacement, and 91.7% +/- 3.2% and 36.4% /- 10% for mitral valve replatement (p = not significant). The freedom from structural valve deterioration in patients older than 70 years o f age was 100% and 93.9% +/- 5.8% at 5 and 10 years, respectively. At 10 years, linearized rate of thromboembolism was 0.73% +/- 0.2% per pa tient-year and freedom from valve-related mortality for all valves was 88.8% +/- 2.8%. The best indication for the implantation of a Mitrofl ow valve is mitral or aortic disease in patients more than 70 years of age.