Stentless porcine valves in the aortic position offer many theoretic a
dvantages, but their clinical performance has not been adequately defi
ned. We evaluated the clinical and echocardiographic results of 103 pa
tients who had aortic valve replacement with the Toronto stentless por
cine valve over a 2-year period. There were 67 men with a mean age of
68 years. The predominant native valve lesion was aortic stenosis (64%
), and 4 patients had prosthetic valve dysfunction. Forty-two patients
had concomitant procedures. The 30-day mortality rate was 3.3% (n = 2
) for isolated valve replacement and 5,8% (n = 6) for the series. The
sole determinant of early death was poor left ventricular function. Th
ere were three late deaths due to nonvalve-related complications over
a median follow-up of 11.87 months. In addition, prosthetic valve endo
carditis developed in 1 patient, necessitating a homograft valve repla
cement at 6 weeks. Doppler echocardiography performed at 3 to 6 months
showed low peak and mean transvalvular gradients, with no substantial
change at 1 year. None of the patients showed signs of clinically sig
nificant aortic regurgitation, although echocardiography demonstrated
trivial or mild regurgitation in 12 patients at discharge or early fol
low-up, which was less marked or absent at 1 year. We conclude that th
e Toronto stentless porcine valve appears to offer promising early res
ults.