This article summarizes current knowledge about social and ethnocultur
al variations in the prevalence of anxiety disorders as well as in the
ir symptomatology and course. Some of the substantial differences in r
ates found in clinical epidemiologic studies probably are related to d
ifferential patterns of help-seeking among different ethnic groups. Cu
ltural factors play an important role in the interpretation of behavio
rs, that is, whether there are reasons in family or social dynamics to
make biased judgments about others. Substantial differences also have
been found in the symptomatology of culture-related forms of anxiety
disorders with variations in content and focus, and in accompanying so
matic manifestations as well. Through the case study of a woman with p
ost-traumatic stress disorder, the social embedding and cultural meani
ng of anxiety in clinical practice are described, and culturally respo
nsive strategies for diagnosis and treatment are outlined. Clinicians
should be encouraged to think of innovative ways of approaching anxiet
y in its social and cultural context.