SICKLE-CELL-ANEMIA, RIGHT ATRIAL THROMBOSIS, AND THE ANTIPHOSPHOLIPIDANTIBODY

Authors
YEGHEN T BENJAMIN S BOYD O PUMPHREY C BEVAN DH
Citation
T. Yeghen et al., SICKLE-CELL-ANEMIA, RIGHT ATRIAL THROMBOSIS, AND THE ANTIPHOSPHOLIPIDANTIBODY, American journal of hematology, 50(1), 1995, pp. 46-48
Citations number
14
Categorie Soggetti
Hematology
Journal title
American journal of hematology → ACNP
ISSN journal
03618609
Volume
50
Issue
1
Year of publication
1995
Pages
46 - 48
Database
ISI
SICI code
0361-8609(1995)50:1<46:SRATAT>2.0.ZU;2-M
Abstract
We report a patient with sickle cell anemia (homozygous Hb SS) and typ ical features of sickle chest syndrome but with no response to exchang e transfusion. A right atrial thrombus was found, and antiphospholipid antibodies were detected in his blood. He responded to thrombolytic t herapy. The relationship between right atrial thrombus and massive pul monary embolus, and the implications of an additional thrombophilic st ate in sickle cell disease are discussed. (C) 1995 Wiley-Liss, Inc.