SUPERCRITICAL-FLUID CHROMATOGRAPHY OF FREE RESIN ACIDS ON AN ODS SILICA-GEL COLUMN

The supercritical fluid chromatographic behaviour of resin acids on an inert ODS-silica gel column using supercritical carbon dioxide as the mobile phase was studied. The separation of resin acids could be achi eved considerably better by using methanol as a modifier. According to these results, the isomers of abietane-type acids could be separated by SFC without derivatization, particularly esterification.